Modafinil (Provigil)

About Modafinil

Modafinil Side Effects

Modafinil Interactions

Modafinil Directions

Modafinil Online - Prescriptions Through AccessMedNet Listings

About Modafinil

This stimulant is prescribed for narcolepsy, and prevents sufferers from falling asleep during the day. The method of action is unclear. This medication only works as long as you take it. Modafinil is not a cure for any condition.

There is some mild risk of psychological dependence with this medication. Never change or increase your dose without the advice of your doctor. Individuals with a history of addictive behavior should be cautious with its use. No symptoms of physical withdrawal have been observed with this medication.

Modafinil is only available by prescription, do not use with either sedatives or other stimulants.

Modafinil Side Effects

Mild Side Effects: Anxiety, decreased appetite, diarrhea, dry mouth or skin, flushing or red skin, headache, insomnia, muscle stiffness, nausea or vomiting, nervousness, rhinitis (runny or stuffy nose), shaking, tingling or burning sensations in the skin, trembling. These effects usually are minor, and tend to go away over time. Speak to your doctor if they should continue, or are bothersome.

Adverse Side Effects: Altered or blurred vision, chills or fever, clumsiness or unsteadiness, confusion, depression, difficulty urinating, dizziness or fainting, increased thirst and urination, memory problems, mood swings, shortness of breath, sore throat, uncontrolled movements of the face or mouth. These conditions should be reported to your doctor, as they may indicate the need for medical treatment.

Overdose: Signs of overdose include high blood pressure, pounding or racing heartbeat, severe insomnia, or uncontrollable agitation or excitement. In an overdose situation, these symptoms would be severe and several will probably occur together. If you, or someone in your household, takes a larger than prescribed dose, seek immediate medical treatment.

Cautions: Modafinil may not be a suitable treatment for all individuals, and others may require precautions to ensure safe and effective treatment. Speak to your doctor regarding a history of any of the following conditions.

  • Allergies: An allergic reaction to a stimulant medication in the past should be discussed with your doctor. If you have an allergic reaction to Modafinil, you should discontinue treatment as soon as your doctor rules out other causes.
  • Asthma: This medication may react with various asthma medications, causing unacceptable levels of CNS stimulation. Speak with your doctor regarding the safety of combining treatments.
  • Heart problems: Heart disease, a recent heart attack, mitral valve prolapse, or any other heart condition are urged to consult their doctor before using this medication. Modafinil may be an unsuitable or dangerous treatment for you.
  • High Blood Pressure: There has been inadequate study on how this condition would be effected.
  • Kidney Disease: It's unclear whether or not problems will result in this case.
  • Liver Disease: Higher blood levels and an increased risk of side effects are possible, a lower dose is recommended.
  • Mental Illness (Severe): Modafinil may worsen these conditions, or bring on a relapse if they are presently under control.
  • Sleep Disorder: If daytime sleepiness is due to some condition such as insomnia, sleep apnea, or restless legs, that interferes with normal sleep, seek treatment for that condition before considering treatment with Modafinil.

Modafinil Online - Prescriptions Through AccessMedNet Listings

Modafinil Interactions

Modafinil may not mix well with all prescription or over the counter treatments. While some medications should not be mixed at all, with others, your doctor may advise you to adjust the dosage or schedule of one of the medications in order to reduce the likelihood of interaction. While you are taking Modafinil, contact your doctor regarding any over the counter or herbal preparation you feel you need.

This medication is a stimulant, and should not generally be mixed with other treatments whose side effects may include racing or irregular heartbeat, insomnia, irritability, or nervousness.

  • Alcohol - This interaction has been insufficiently studied. Avoid alcohol during treatment, as unpredictable side effects may occur.
  • Amphetamines - Stimulants of this class may cause unacceptable CNS stimulation when mixed with modafinil. There may be severe interaction effects including insomnia, irregular heartbeat, irritability, nervousness, or racing heartbeat.
  • Anticonvulsants - Medications like Cerebyx (fosphenytoin), Dilantin (phenytoin), Mesantoin (mephenytoin), or Phenobarbitol may require dosage adjustments.
  • Asthma medication - Possible risk of severe interaction effects including insomnia, irregular heartbeat, irritability, nervousness, racing heartbeat, or seizure.
  • Birth Control (oral contraceptives, contraceptive implants) - Hormone treatments designed to prevent pregnancy may become less effective in combination with this medication. Use an additional form of contraception (condom, spermicidal jelly, sponge, cervical cap) during intercourse while taking this medication, and for another month after modafinil treatment ends.
  • Caffeine - Increased risk of racing heartbeat, nervousness, or other undesirable side effects.
  • Cesamet (nabilone)
  • Cocaine - May dangerously overstimulate the nervous system, do not combine. Avoid taking all street drugs while using modafinil, as the results could be dangerous or life-threatening.
  • Cold medication - Possible risk of severe interaction effects including insomnia, irregular heartbeat, irritability, nervousness, or racing heartbeat.
  • Coumadin (warfarin) - Dosage adjustments may be necessary.
  • Cylert (pemoline) - May overstimulate the nervous system.
  • Diet pills - This drug combination could be dangerous, avoid stimulant diet pills like Meridia (sibutramine) while undergoing treatment with modafinil. Do not use herbal diet preparations, as they are likely to contain one or more stimulants.
  • Inderal (propranolol) - Dosage adjustments may be necessary.
  • MAO inhibitors - Modafinil must never be mixed with MAO (monoamine oxidase) inhibitors, a class of antidepressants and antisenility drugs, such as Eldepryl (selegiline), Furoxone (furazolidone), Nardil (phenelzine), Marplan (isocarboxazid), or Parnate (tranylcypromine). These medications react badly with certain similar drugs, and have not been adequately tested in combination with modafinil. Avoid using modafinil within two weeks of an MAO inhibitor.
  • Ritalin (methylphenidate) - May increase CNS stimulant effects like insomnia or nervousness.
  • Sandimmune (cyclosporine) - Dosage may need adjustment.
  • Street drugs - Be particularly careful not to use modafinil with cocaine, amphetamines (speed), or PCP, as these drugs are powerful stimulants. Serious or fatal heart complications could result from a combination. Individuals should avoid mixing street drugs with all prescription treatments, as the interactions are rarely adequately studied, and could be very dangerous.
  • Symmetrel (amantadine) - Can increase CNS stimulation.
  • Tegretol (carbamazepine) - Consult your doctor.
  • Tricyclic antidepressants such as Elavil (amitriptyline), Asendin (amoxapine), Anafranil (clomipramine), Pertofrane or Norpramin (desipramine), Sinequan (doxepin), Tofranil (imipramine), Aventyl or Pamelor (nortriptyline), Vivactil (protriptyline), and Surmontil (trimipramine), may build up in the body when used with modafinil. Undesirable side effects, such as increased blood pressure, could result.
  • Ulone (chlophedianol) - May overstimulate the nervous system.
  • Valium (diazepam) - Dosage adjustments may be necessary.
  • Wellbutrin/Zyban (bupropion) - May increase risk of serious side effects such as irregular heartbeat, or other overstimulation of the circulatory system.

Modafinil Directions

Modafinil is available in 100 mg and 200 mg tablets. The standard dose is 200 mg, taken once daily in the morning. Individuals with impaired kidney or liver function, or who are otherwise highly sensitive to stimulants, may be prescribed a dose of 100 mg. If the directions you receive from your doctor are different, follow them exactly.

This medication is usually taken once daily in the morning, ask your doctor if they wish you to follow any additional instructions regarding your schedule and the manner of use.

If you miss a dose, take it as soon as possible if you remember before noon. Taking your medication any later in the day can increase the likelihood of insomnia. If you miss skip a dose, resume your regular dosing schedule, ignoring the missed dose. Do not take double doses of this medication.

If insomnia results from taking this medication, speak to your doctor about adjusting your dosage or medication schedule.

Store Modafinil away from direct light and heat. Store in a dry location; avoid storing it in the bathroom, near sinks, or other areas where it may become damp. Do not use after the expiration date.

Keep Modafinil away from children; both when storing it, and when discarding any unused medication. If the prescription is for a child, carefully supervise its use.

Pregnant or nursing women and individuals under 16 should not use this medication. Seniors will usually be prescribed a reduced dose.

Modafinil Online - Prescriptions Through AccessMedNet Listings

Provigil is a trademark of Cephalon

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This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. Any dosages mentioned are general guidelines only, please follow the directions of your doctor or pharmacist exactly when taking medication. We have made every effort to ensure that this information is accurate, but only your doctor can say if a medication, or drug combination, is safe for you. Information intended for US residents only.
 
     
 
 

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